Sinead M. Walsh

Sinead M. Walsh

Lecturer and Lab Instructor, Assistant Professor of Chemistry, Organic Chemistry Lab Co-Ordinator

swalsh@stonehill.edu
508-565-1852
Shields 302
Chemistry

Biography

Dr. Sinead Walsh received her B.S. in Chemistry in 1993 from University College, Dublin in Ireland. She then earned her Ph.D. also at University College, Dublin where she worked under the guidance of Dr. Rory A. More O’Ferrall. Her research investigated the catalysis of tautomerization of heterocyclic ketones, and E to Z isomerisation equilibria for enaminone tautomers. She also studied the use of induced deuterium shifts as a method to distinguish between enol and enaminone tautomers by C-13 NMR. 

Dr. Walsh then joined Bristol-Myers Squibb as a process development chemist and was involved in the development and scale-up of various active pharmaceutical ingredients including a novel anti-HIV protease inhibitor, working in Ireland and Puerto Rico. In 2000 she joined Rhodia ChiRex in Boston, where she performed process development and optimization services for pharmaceutical clients. Dr. Walsh joined the faculty at Stonehill College as an adjunct professor in 2010 and became a full-time assistant professor in 2020. 

Education

  • B.S. Chemistry, University College, Dublin, Ireland 
  • Ph.D. Chemistry, University College, Dublin, Ireland 

Courses Taught  

  • General Chemistry I
  • General Chemistry II Laboratory
  • Organic Chemistry I & Laboratory
  • Organic Chemistry II & Laboratory

Selected Publications, Articles & Presentations

  • Proton Activating Factors and Keto-enol-zwitterion Tautomerism of 2-, 3-, and 4-phenylacetyl pyridines. Geraldine M. McCann, Rory A. More O’Ferrall and Sinead M. Walsh, J. Chem. Soc, Perkin Trans 2, 1997, 2761-2772. doi.org/10.1039/A701546A 
  • Binding of Proton and Zinc Ions to Transition States for Tautomerisation of a-Heterocyclic Ketones: Implications for Enzymatic Reactions. G. McCann, R.A. More O'Ferrall, S.J. Eustace, B.A. Murray and S. Walsh, J. Phys. Org. Chem., 1998, 11, 519-528. doi.org/10.1002/(SICI)1099-1395(199808/09)11:8/9<519::AID-POC58>3.0.CO;2-Y 
  • A Study of the Enol-Enaminone Tautomerisation of α-Heterocyclic Ketones by Deuterium Effects of 13C Chemical Shifts. A.R. Katritzky, Ion Ghiviriga, Daniela C. Oniciu, Rory A. More O’Ferrall and S. M. Walsh, J. Chem. Soc, Perkin Trans 2, 1997, 2605 -2608. doi.org/10.1039/A705235I 

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